Biological factors consist of anything physical that can cause adverse effects on a person’s Mental Health. This includes genetics, prenatal damage, infections, exposure to toxins, brain defects or injuries, chemical imbalances, and substance abuse. Many professionals believe that the sole cause of mental disorders is based upon the biology of the brain and the nervous system. Scientists have learned that serotonin receptors in the brain increase their activity in persons with major depression and suicidality, which explains why medications that desensitize or down-regulate these receptors (such as the serotonin re-uptake inhibitors, or SSRIs) have been found effective in treating depression. Currently, studies are underway to examine to what extent medications like SSRIs can reduce suicidal behavior. One of the goals of understanding the biology of suicidal behavior is to improve treatments.

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